2-Fluoro-4-nitrobenzoyl chloride
2-Fluoro-4-nitrobenzoyl chloride
CAS: 403-23-6
Molecular Formula: C7H3ClFNO3
2-Fluoro-4-nitrobenzoyl chloride - Names and Identifiers
| Name | 2-Fluoro-4-nitrobenzoyl chloride |
| Synonyms | 2-Fluoro-4-nitrobenzoyl chloride Benzoyl chloride, 2-fluoro-4-nitro- |
| CAS | 403-23-6 |
2-Fluoro-4-nitrobenzoyl chloride - Physico-chemical Properties
| Molecular Formula | C7H3ClFNO3 |
| Molar Mass | 203.55 |
| Sensitive | IRRITANT |
| MDL | MFCD12025048 |
2-Fluoro-4-nitrobenzoyl chloride - Introduction
2-Fluoro-4-nitrobenzoyl chloride (2-fluoro-4-nitrobenzoyl chloride) is an organic compound with the chemical formula C7H3ClFNO3. The following is a detailed description of its nature, use, formulation and safety information:
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 62-64°C
-Boiling point: 310°C
-Density: 1.62g/cm3
-Solubility: Soluble in organic solvents such as dichloromethane and ether, slightly soluble in water
-Nature: It is a flammable compound, irritating and corrosive.
Use:
- 2-Fluoro-4-nitrobenzoyl chloride is an important intermediate in organic synthesis. It can be used to synthesize a variety of drugs and pesticides, such as antibiotics, plant growth regulators, etc.
-Due to its special chemical properties, it can also be used as an organic synthesis reagent and catalyst for the synthesis of various organic compounds.
Preparation Method:
2-Fluoro-4-nitrobenzoyl chloride is prepared as follows:
1. First, 2-fluoro-4-nitrobenzoic acid is reacted with thionyl chloride to prepare 2-fluoro-4-nitrobenzimide.
2. Then, 2-fluoro-4-nitrobenzimide is reacted with excess thionyl chloride at 40-60°C to generate 2-fluoro-4-nitrobenzoyl chloride.
3. Finally, 2-fluoro-4-nitrobenzoyl chloride was purified by crystallization or extraction.
Safety Information:
- 2-Fluoro-4-nitrobenzoyl chloride is an organic compound that is irritating and corrosive. Appropriate personal protective equipment, such as lab gloves, goggles and protective clothing, should be worn during operation.
-It is a flammable compound, avoid exposure to open flames and high temperatures.
-When storing, it should be stored in a dry, cool, well-ventilated place, and away from combustibles and oxidants.
-When handling or disposing, local regulations and safe operating procedures should be followed to prevent harm to humans and the environment.
Please note that for safe handling and storage of chemicals, always refer to the appropriate safety data sheets and safety information provided by the chemical manufacturer.
Nature:
-Appearance: Colorless to light yellow crystal
-Melting point: 62-64°C
-Boiling point: 310°C
-Density: 1.62g/cm3
-Solubility: Soluble in organic solvents such as dichloromethane and ether, slightly soluble in water
-Nature: It is a flammable compound, irritating and corrosive.
Use:
- 2-Fluoro-4-nitrobenzoyl chloride is an important intermediate in organic synthesis. It can be used to synthesize a variety of drugs and pesticides, such as antibiotics, plant growth regulators, etc.
-Due to its special chemical properties, it can also be used as an organic synthesis reagent and catalyst for the synthesis of various organic compounds.
Preparation Method:
2-Fluoro-4-nitrobenzoyl chloride is prepared as follows:
1. First, 2-fluoro-4-nitrobenzoic acid is reacted with thionyl chloride to prepare 2-fluoro-4-nitrobenzimide.
2. Then, 2-fluoro-4-nitrobenzimide is reacted with excess thionyl chloride at 40-60°C to generate 2-fluoro-4-nitrobenzoyl chloride.
3. Finally, 2-fluoro-4-nitrobenzoyl chloride was purified by crystallization or extraction.
Safety Information:
- 2-Fluoro-4-nitrobenzoyl chloride is an organic compound that is irritating and corrosive. Appropriate personal protective equipment, such as lab gloves, goggles and protective clothing, should be worn during operation.
-It is a flammable compound, avoid exposure to open flames and high temperatures.
-When storing, it should be stored in a dry, cool, well-ventilated place, and away from combustibles and oxidants.
-When handling or disposing, local regulations and safe operating procedures should be followed to prevent harm to humans and the environment.
Please note that for safe handling and storage of chemicals, always refer to the appropriate safety data sheets and safety information provided by the chemical manufacturer.
Last Update：2024-04-09 21:04:16
